10-Hydroxycamptothecin CAS 19685-09-7

Deskripsyon pwodwi:

Non pwodwi: 10-Hydroxycamptothecin CAS NON: 19685-09-7

Sinonim:

Camptothecin, hydroxy;

Hydroxycamptothecine;

10-OH-camptothecin;

Chimik& Pwopriyete fizik:

Aparans: Solid jòn

Egzamen: ≥99.0%

Dansite: 1.60

Pwen fizyon: 265-270 ℃

Bouyi Point: 820.7 ± 65.0 ℃ (prevwa)

Tanp Depo: Kenbe nan kote ki fè nwa, atmosfè inaktif, magazen nan frizè, anba -20 ℃

Enfòmasyon sou sekirite:

HS Kòd: 2934999090

Deklarasyon Sekirite S24 / 25

Yon derive Camptothecin; yon inibitè topoisomerase pou terapi kansè. (S) -10-Hydroxycamptothecin se yon ajan terapi klinik kont hepatoma.IC50 valè: Sib: In vitro: In vitro, 10-hydroxycamptothecin nanosuspensions lage dwòg la enkapsule ak prèske zewo-lòd sinetik, ak liberasyon an akimile rive nan 90% nan 72 èdtan. Nan vitro tès sitotoksisite te montre ke 10-hydroxycamptothecin nanosuspensions yo te siyifikativman amelyore citotoxicity kont selil HepG2 konpare ak piki yo 10-hydroxycamptothecin Commerce disponib [1]. te montre ke Kontrèman a piki yo 10-hydroxycamptothecin, nanosuspensions yo 10-hydroxycamptothecin ekspoze siyifikativman amelyore biodistribisyon, patikilyèman nan poumon an (393.40-pliye AUC0-24 h, fwa (192.35-pliye AUC0-24 h, larat (141.67-pliye AUC0 –24 h ak timè (64,21-pliye AUC0-24 h. 10-hydroxycamptothecin nanosuspensions yo te montre tou amelyore antitumor efikasite ki ka geri ou sou piki yo (89.83% vs 30.56%).

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Baj popilè: 10-hydroxycamptothecin cas 19685-09-7, manifaktirè, founisè, faktori, achte, nan stock

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