(1R,2S,5S)-N-((S)-1-amino-1-oxo-3-((S)-2-oxopyrrolidin-3-il)propan{ {10}}il)-3-((S)-3,3-dimetil-2-(2,2,2-trifluoroacetamido)butanoyl )-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide CAS 2755812-81-6

Deskripsyon Product:

ProductName:(1R,2S,5S)-N-((S)-1-amino-1-oxo-3-((S)-2-oxopyrrolidin-3-il) propan{{10}}il)-3-((S)-3,3-dimetil-2-(2,2,2-trifluoroacetamido )butanoyl)-6,6-dimetil-3-azabicyclo[3.1.0]hexane-2-carboxamide CAS 2755812-81-6

 

Sinonim:

{{0}}Azabicyclo[3.1.0]hexane-2-carboxamide,N-[(1S)-2-amino-2-oxo-1-[[(3S) )-2-oxo-3-pirolidinil]methyl]etil]-3-[(2S)-3,3-dimethyl-1-oxo-2- [(2,2,2-trifluoroacetyl)amino]butil]-6,6-dimetil-, (1R,2S,5S)-;

 

Pwopriyete Chimik ak Fizik

Aparans: Pale jòn a Pale bèj solid

Esè: 99% +

Pka:10.26±0.46

Pwen bouyi:787.5±60.0 degre

Dansite: 1.288±0.06g/cm³

 

Aplikasyon

Li se yon entèmedyè nan Parovade.Paxlovid se yon konbinezon antiviral ki fòme ak de tablèt. Yon grenn se Nirmatrelvir (150mg), yon inibitè nan 3CL proteaz (ke yo rele tou proteaz prensipal, Mpro) nan nouvo coronavirus la. 3CL proteaz se yon proteaz kle ki idrolize RNA-kode pwoteyin polyprecursor pou pwodui pwoteyin fonksyonèl pandan replikasyon coronavirus la. Nematavir ka anpeche replikasyon coronavirus SARS-CoV-2 lè li anpeche 3CL proteaz. Lòt grenn nan se Ritonavir (100mg), yon inibitè pwoteaz VIH-1 ak CYP3A4 (anzim cytochrome P4503A4). Malgre ke Ritonavir pa aktif kont SARS-CoV-2Mpro, li anpeche metabolis CYP3A4-medyatè nematavir pou ede li rete aktif nan kò a pi lontan nan pi gwo konsantrasyon.

 

Si w enterese nan pwodwi nou yo oswa si w gen nenpòt kesyon, tanpri ou lib pou kontakte nou!

 

Pwodwi anba patant yo ofri pou rezon R & D sèlman. Sepandan, responsablite final la se sèlman nan achtè a.

Baj popilè: (1r,2s,5s)-n-((s)-1-amino-1-oxo-3-((yo)-2-oxopyrrolidin-3-il)propan{ {10}}il)-3-((yo)-3,3-dimetil-2-(2,2,2-trifluoroacetamido)butanoyl )-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide cas 2755812-81-6, manifaktirè, founisè, faktori, achte, nan stock

• On: (1R,2S,5S)-3-((S)-3,3-dimetil-2-(2,2,2-trifluoroacetamido)Chemicalbookbutanoyl){{1 0}},6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylicacid CAS 2755812-45-2
• Pwochen: 6,6-dimethyl-3-azabicyclo[3.1.0]hexane,hydrochloride CAS {{}}