ER-886046-00 CAS 1369489-71-3

Deskripsyon pwodwi:

Non pwodwi: ER-886046-00 CAS NON: 1369489-71-3

Sinonim:

(S) -4- (1- (3- (difluoromethyl) -1-methyl-5- (3- (trifluoromethyl) phenoxy) -1H-pyrazole-4-carboxamido) ethyl) benzoic acid;

E7046;

Benzoicacid, 4 - [(1S) -1 - [[[3- (difluoromethyl) -1-methyl-5- [3- (trifluoromethyl) phenoxy] -1H-pyrazol-4-il] carbonyl] amino] ethyl] - ;

Chimik& Pwopriyete fizik:

Aparans: Solid oswa poud

Egzamen: ≥99.0%

Dansite: 1.43 ± 0.1 g / cm3 (prevwa)

Pwen bouyi: 594,8 ± 50,0 ℃ (prevwa)

Flash Point: 313,5 ± 30,1 ℃

PKa: 4.17 ± 0.10 (prevwa)

Presyon vapè: 0.0 ± 1.8 mmHg nan 25 ℃

Endèks Refraksyon: 1.564

E7046 se yon antagonist EP4 oralman biodisponib ak espesifik, ak IC50 nan 13.5 nM ak Ki nan 23.14 nM, ki montre aktivite anti-timè. E-7046 se yon antagonis espesifik nan kalite 4 prostaglandin E2 (PGE2) reseptè EP4 (IC₅₀=13.5 nM). Li posede siyifikatif aktivite kwasans antitumoral nan plizyè modèl timè preklinik nan modil selil myeloid, ki gen ladan timè ki asosye macrophages ak myeloid-sòti selil suppressor.

Si ou enterese nan pwodwi nou yo oswa ou gen nenpòt kesyon, tanpri ou lib pou kontakte nou!

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Baj popilè: er-886046-00 cas 1369489-71-3, manifaktirè, founisè, faktori, achte, nan stock

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