Perampanel CAS 380917-97-5

Deskripsyon pwodwi:

Non pwodwi: Perampanel CAS NON: 380917-97-5

Sinonim:

3-(2-Cyanophenyl)-1-phenyl-5-(2-piridil)-1,2-dihydropyridin-2-yon;

2-(6'-Oxo-1'-phenyl-1',6'-dihydro-[2,3'-bipiridin]-5'-il)benzonitril;

Benzonitrile, 2-(1',6'-dihydro-6'-oxo-1'-phenyl[2,3'-bipiridin]-5'-il)-;

Chimik& Pwopriyete fizik:

Aparans: solid cristalline

Esè: ≥99.0%

Dansite: 1.31±0.1 g/cm3 (Predi)

Pwen bouyi: 619.1±55.0 ℃ (Prevwa)

Flash Point: 328.2±31.5℃

Presyon vapè: 0.0±1.8 mmHg nan 25℃

Endèks refraksyon: 1.706

Perampanel se premye antagonist reseptè α-amino-3-hydroxy-5-methylisooxazol-4-propionic asid (AMPA) ki pa konpetitif nan mond lan devlope pa EISAIINC. Li te apwouve pa Ewopeyen EMA ak Ameriken FDA an Jiyè ak Oktòb 2012, respektivman. Li se itilize pou tretman adjunctive nan pasyan epilepsi pasyèl kriz malkadi ki gen plis pase 12 ane ki gen laj ak oswa san segondè gwo kriz sistemik. Nan dat 22 jen 2015, Eisai te anonse ke US Food and Drug Administration (FDA) te apwouve endikasyon elaji pou Pirampanet idrat (Fycompa) kòm yon tretman adjuntif pou prensipal kriz jeneralize tonik-klonik nan pasyan ki gen 12 zan oswa plis.

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Baj popilè: perampanel cas 380917-97-5, manifaktirè, founisè, faktori, achte, nan stock

• On: 1-Phenyl-5-(pyridin-2-yl)-1, 2-dihydropyridin-2-yon CAS 381725-50-4
• Pwochen: 1-(1-(tèt-Butoxicarbonyl)piperidin-4-yl)-1H-pirazol-4-ylboronic Asid CAS 1190875-39-8