(R) -Rivaxaban CAS 865479-71-6

Pwodwi Deskripsyon:

Non pwodwi: (R) -Rivaroxaban CAS NON: 865479-71-6

 

Sinonim:

5-R-Rivaroxaban;

5-chloro-N-[[(5R) -2-oxo-3-[4-(3-oxompholin-4-yl) phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-kaboxamide;

2-Thiophenecarboxamide,5-chloro-N-[[(5R) -2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-5-oxazolidinyl]-;

 

Chimik & Pwopriyete fizik:

Aparans : poud blan

Assay: ≥97.0%

Dansite: 1.46g / cm3

Bouyi pwen: 732.6 ° Cat 760 mmHg

Flash Point: 396.9 ° C

 

5-R-Rivaroxaban se (R) enantiomer de Rivaroxaban. Rivaxaban (BAY 59-7939) se yon tre ki pisan ak selektif, fakte direk Xa (FXa) inibitor, reyalize yon pwogre fo nan potansyel anti-FXa (IC50 0.7 nM; Ki 0.4 nM).

Rivaroxaban (BAY 59-7939) se yon oral, fakte direk Xa (FXa) inibitor nan devlopman pou prevansyon an ak tretman nan trombosis ateryel ak venn. Rivaroxaban konpetitivman inibit Imen FXa (Ki 0.4 nM) ak >10 000-pliye pi gwo seleksyon pase pou lot pwotez serye; li tou inibit aktivite protrombinase (IC50 2.1 nM). Rivaroxaban inhibits andogenous FXa pi red nan moun ak lapen plasma (IC50 NM) pase plasma rat (IC50 290 nM). Li demontre efe anticoagulant nan plasma imen, doubling tan protronbin (PT) ak aktive pasyel tan tronboplastin nan 0.23 ak 0.69 μM, respektivman.

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Baj popilè: (r) -rivaxaban cas 865479-71-6, manifaktire, founise, faktori, achte, nan stock

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