Safinamide CAS 133865-89-1

Pwodwi Deskripsyon:

Non pwodwi: Safinamide CAS NON: 133865-89-1

 

Sinonim:

Safinamide, Baz Safinamide;

Safinamide Entemedye 2;

(S)-(+)-2-[4-(3-Fluorobenzyloxyloxyloxy)benzylamino]propanamice methanfonate;

 

Chimik & Pwopriyete fizik:

Aparans: blan a solid blan

Assay: ≥99.00%

Dansite: 1.189 g / cm3

Bouyi pwen: 476.7 ° C nan 760 mmHg

Flash Point: 242.1±27.3° C

Endeks refraktif: 1.569

Vapore Presyon: 2.98E-09mmHg nan 25 ° C

 

Safinamide (EMD 1195686; FCE 26743) selektivman ak reversibly inibit MAO-B ak IC50 nan 98 NM, ekspozisyon 5918-pliye seleksyon kont MAO-A. IC50 vale: 98 nM [1] Sib: MAO-BSafinamide (EMD 1195686; FCE 26743; ) se yon konsantrasyon oxidase tre selektif ak reversible B (MAO-B) inibitor ki ogmante konsantrasyon dopamine neostriatal. Anplis de sa, Safinamide (EMD 1195686; FCE 26743; ) se voltaj-depandan sodyom ak kalsyom blokaj kanal. Safinamide (EMD 1195686; FCE 26743; ) paret mare nan sit la batrachotoxin-sansib 2 nan chanel yo sodyom voltaj-sansib. Safinamide blok N ak L-kalite chanel kalsyom ak inibit glutamate ak aspatat lage soti nan teminal sinaptik.

 

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Baj popilè: safinamide cas 133865-89-1, manifaktire, founise, faktori, achte, nan stock

• On: 2-Bromo-2- (2-fluorophenyl) -1-cyclopropylethanone CAS 204205-33-4
• Pwochen: 4- (3-Fluorobenzyloxy) benzaldeyid CAS 66742-57-2