Spironolactone CAS 52-01-7

Pwodwi deskripsyon:

Non pwodwi: Spironolactone CAS non: 52-01-7

 

Synonyms:

7α-Acetylthio-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic asid γ-lactone;

S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a] phenanthrene-17,2 '-oxolane]-7-yl] ethanethioate;

7α-Acetylthiospirolactone;

 

Chimik &PhysicalProperties:

Aparans: blan poud

Asdi: ≥99,0%

Dansite: 1.24 g/cm3

Boiling Point: 597 ° c nan 760mmHg

Wouj Point: 198-207 ° c

Flash Point: 302.3 ° c

Refractive index:-36 ° (C = 1, CHCl3)

Dlo slubility: prexke ensolib

Estabilite: ki estab anba tanperati nomal ak presyon.

Kondisyon depo: kenbe veso femen le yo pa nan itilize. Magazen nan yon fre, sek, byen aere zon lwen soti nan sibstans enkonpatib.

 

Enfomasyon sou sekirite:

RTECS: TU4725000

Deklarasyon sekirite: S53-S22-S36/37/39-S45

HS Kod: 2937290090

WGK Almay: 3

Risk deklarasyon: R40; R60

Danje Kod: T

 

Spironolactone se yon antagonis ki pisan nan récepteurs monn mal la. Sib: Monn mal ReceptorSpironolactone se yon potasyom sparing diretik ki aji pa opozisyon nan aldosteron nan ren nan distal tubules. Li se itilize sitou nan tretman an nan ede mwen refractory nan pasyan ki gen echek ke konjestif, sendwom nephrotic, oswa hepatic siwoz. Efe li yo sou sistem nan andokrin yo itilize nan tretman yo nan tis ak ti bouton kwasans men yo ka mennen nan Efe Efe negatif. 5% okalize spironolactone krem travay kom yon antiandrogen nan glann sebaceous imen, konpetisyon ak resepte DHT ak pwodwi yon diminye nan labelled DHT. Nan konsantrasyon yo itilize Efe a te selman lokal. Pa gen okenn lot Efe sou kote yo te anrejistre pandan tou de etid. Pasyan ki te resevwa spironolactone te gen yon amelyorasyon enpotan nan sentom yo nan echek ke, kom evalye sou baz la nan asosyasyon ke New York la fonksyonel klas (P<0.001). gynecomastia="" or="" breast="" pain="" was="" reported="" in="" 10="" percent="" of="" men="" who="" were="" treated="" with="" spironolactone,="" as="" compared="" with="" 1="" percent="" of="" men="" in="" the="" placebo="" group=""><0.001). the="" incidence="" of="" serious="" hyperkalemia="" was="" minimal="" in="" both="" groups="" of="">

 

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Baj popilè: spironolactone cas 52-01-7, manifaktire, founise, faktori, achte, an aksyon

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