Tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-prayzol-1-yl]piperidine-1-kaboxylate CAS 87739-74-1

Pwodwi Deskripsyon:

Non pwodwi: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1H-pyrazol-1-yl]piperidine-1-kaboksilate CAS 877399-74-1

Sinonim:

4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxborolan-2-yl) -pyrazol-1-yl]-piperidin-1-1-kaboksilik asid te-butyl ester;

Chimik & Pwopriyete fizik:

Aparans: poud blan

Assay: ≥99.0%

Dansite: 1.14g / cm3

Bouyi pwen: 492.8 ° C nan 760 mmHg

Flash Point: 251.8 ° C

Krizotinib entemedye.

Crizotinib se yon ti molekil tirosin kinaz inibitor (TKI) ki vize anaplastik kinaz aaplastic (ALK), ROS1, ak yon lot resepte oncogene tyrosine kinaz MET. Kapsil Crizotinib ka itilize pou tretman an nan lokalman avanse oswa metastatik kanse poumon ki pa piti poumon selil (NSCLC) pasyan ki pozitif pou kinaz lenfom anaplastik (ALK) detemine pa metod tes SFDA-apwouve. Apwobasyon nan endikasyon sa a sitou ki baze sou to a repons objektif (ORR) ak pwogresyon-gratis siviv (PFS) prev. Koulye a, pa gen okenn prev nan benefis siviv (OS) nan pwodwi sa a.

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Baj popilè: tert-butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) -1h-prayzol-1-yl]piperidine-1-kaboxylate cas 87739-74-1, manifaktire, founise, faktori, achte, nan stock

• On: Tert-butil 4- (4-iodo-1H-pirazol-1-il) piperidin-1-karboksilat CAS 877399-73-0
• Pwochen: Crizotinib CAS 877399-52-5