1-cyclopropyl-2-(2-fluorophenyl) ethanone CAS 150322-73-9

Pwodwi deskripsyon:

Non pwodwi: 1-cyclopropyl-2-(2-fluorophenyl) ethanone CAS non: 150322-73-9

 

 

Synonyms:

Cyclopropyl-2-fluoro benzyl ketone;

Ethanone, 1-cyclopropyl-2-(2-fluorophenyl)-;

 

 

Chimik & pwopriyete fizik:

Aparans: tankou jon lwil oliv

Épreuves: ≥ 99,0%

Dansite: 1.192 g/cm3

Bouyi pwen: 253.6 ° c nan 760 mmHg

Flash pwen: 107.9 ° c

 

 

1-cyclopropyl-2-(2-fluorophenyl) ethanone se itilize nan prasugrel entemedye.

Prasugrel se yon thienopyridine ki rele Dwog ki devlope pa Eli Lilly ak Japone pharmaceutique manifakti Daiichi Sankyo (Daiichi Sankyo). Li se yon Dwog proki metabolize pa cytochrome P450 nan fwa a yo fome yon Molekil aktif. P2Y12 récepteurs mare pou fe egzesis aktivite anti-agrégation.

Sou desanm 18, 2008, Prasugrel te resevwa premye rekonesans entenasyonal li yo. Komite Ewopeyen pou swen medikal Ewopeyen an pou pwodwi Medical (CHMP) rekomande apwobasyon Dwog la. Nan fen mwa fevriye 2009, li te apwouve pa Komisyon Ewopeyen an.

Nan Ewop, li vann anba non an komes Efient epi li se itilize yo trete egi sendwom riz kadyak/. Prasugrel ap travay pa bloke P2Y12 adenosine diresepte a sou sifas la ki te soti nan empêcher ki nan deklanchman ak konkouran agrégation. Yo te itilize Dwog ansyen yo pou anpeche agrégation yo oswa rete soude ansanm. Si agrégation ki lakoz ateryel lokaj ak ka lakoz maladi ke oswa konjesyon serebral.

Sou jiye 10, 2009, manje a ak administrasyon Dwog apwouve prasugrel tablet pou pasyan sibi angioplasty diminye risk pou yo tronbozi.

Li te apwouve nan Kanada nan mwa avril 2010 pou tretman nan sendwom egi riz kadyak/.

 

 

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Baj popilè: 1-cyclopropyl-2-(2-fluorophenyl) ethanone cas 150322-73-9, konpayi fabrikasyon, founise, faktori, achte, nan Stock

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