(1R,2S,5S)-methyl 6,6-dimethyl-3-aza-biscyclo[3.1.0]hexane-2-carboxylate Hydrochloride CAS 565456-77-1

Deskripsyon Product:

(1R,2S,5S)-methyl6,6-dimethyl-3-aza-biscyclo[3.1.{0]hexane-2-carboxylate hydrochloride CAS 565456-77-1

 

Sinonim:

Boceprevir InterMediates;

Methyl (1r,2s,5s)-6,{4}dimethyl{{{5{5}}azabicyclo[3.1.0]hexane-2-carboxylate;

 

Pwopriyete Chimik ak Fizik

Tanperati depo: Atmosfè inaktif, Tanperati chanm

Fòm: solid

Koulè: jòn pal

InChI:InChI=1/C9H15NO2.ClH/c1-9(2)5-4-10-7(6(5)9)8(11)12-3;/h{{13} },10H,4H2,1-3H3;1H/t5-,6-,7-;/s3

InchiKey:FKVUDBWXNAFSPB-AUBOPKACNA-N

SOURI:C([C@H]1NC[C@@H]2C(C)(C)[C@H]12)(=O)OC.Cl |&1:1,4,8, r|

 

Enfòmasyon sou Sekirite

Kòd HS: 2933998090

 

Itilizasyon:

Entèmedyè Boprevir, sètadi (1R, 2S, 5S) -6,6-dimethyl-3-azabicyclic [3.1.0] hexane-2-carboxylic acid methyl ester idroklorid, se chèn bò kote Boprevir. Pramivir se yon inibitè proteaz epatit C devlope pa Schering Plough, ki ka itilize kòm dwòg prensipal nan terapi trip (ak polyethylene glycol - Se konbinezon an nan interferon ak ribavirin yo itilize pou tretman CHC jèn kalite I epatit kwonik. Konbinezon an nan twa dwòg ka geri plis pase 60% nan pasyan yo, epi yo itilize polyethylene glycol pou kont li - Pousantaj geri a nan interferon oswa ribavirin se 2 a 3 fwa pi wo, ak boprivir ka amelyore to a geri pandan y ap tou diminye tan tretman an.

 

Boceprevir (non komèsyal Boceprevir), ak non chimik (1S, 2S, 5S) - N - (4-amino-1-cyclobutyl-3,4-dioxobutane{{9 }}yl) {{1{{20}}}} [(2S) -2- (tèt butilamino) -3,3-dimethylbutyryl] -6 ,6-dimethyl-3-azabicyclo [3.1.0] hexane-2-formamid, se yon inibitè proteaz epatit C devlope pa American Chemicalbook Schering Plough, Li ka itilize kòm dwòg prensipal pou terapi trip. (an konbinezon ak pegylated interferon ak ribavirin) pou tretman CHC jèn tip I kwonik epatit. Konbinezon an nan twa dwòg ka geri plis pase 60% nan pasyan yo, epi yo itilize polyethylene glycol pou kont li - Pousantaj geri a nan interferon oswa ribavirin se 2 a 3 fwa pi wo, ak boprivir ka amelyore pousantaj geri a pandan y ap diminye tan tretman an. Administrasyon Ameriken Food and Drug Administration (FDA) te otorize medikaman an nan dat 13 me 2011. 1R, 2S, 5S) -6,6-dimethyl-3-azabicyclic [3.1.0 ] hexane-2-asid carboxylic methyl ester hydrochloride (I) se kle entèmedyè ak pri ki pi wo nan pwosesis sentèz bò chèn Boprevir la.

 

Pwodui sa a se yon derive azabicyclohexane, ki ka itilize pou prepare viris epatit C (HCV) NS3 serine proteaz inhibitor. Objektif: Entèmedyè Boprevir se yon entèmedyè òganik entèmedyè ak yon entèmedyè pharmaceutique, ki ka itilize nan rechèch laboratwa ak pwosesis devlopman ak pwosesis pwodiksyon chimik, sitou kòm yon sibstans estanda ak referans.

 

Si w enterese nan pwodwi nou yo oswa si w gen nenpòt kesyon, tanpri ou lib pou kontakte nou!

 

Pwodwi anba patant yo ofri pou rezon R & D sèlman. Sepandan, responsablite final la se sèlman nan achtè a.

Baj popilè: (1r,2s,5s)-methyl 6,6-dimethyl-3-aza-biscyclo[3.1.0]hexane-2-carboxylate hydrochloride cas 565456-77-1, manifakti , founisè, faktori, achte, nan stock

• On: N-Boc-L-Tert-Leucine CAS 62965-35-9
• Pwochen: 6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9