2-(4-ethylphenyl){2{2}methylpropanoic Acid CAS 1247119-83-0}

Deskripsyon Product:

Non pwodwi:2-(4-ethylphenyl)-2-methylpropanoic asid CAS 1247119-83-0

 

Sinonim:

{[(2s)-3,3-dimethyl-2-oksiranil]methyl}-7-methoxy-2h-chromen-2-yon sèl;

4-etil-, -dimethyl-Benzeneacetic asid;

 

Pwopriyete Chimik ak Fizik

Aparans: N/A

Esè: 99% +

Pwen bouyi: 302.8±11.0 degre

Dansite: 1.047±0.06 g/cm³

Pka:4.48±{2{2}}.10

 

Aplikasyon

Li se yon entèmedyè nan alectinib. Alectinib (CH5424802) se yon inibitè ALK ki pisan ak yon IC50 nan 1.9nM, sansib a mutan L1Chemicalbook196M, ak plis selektif nan ALK pase PF-02341066, NVP- TAE684 ak PHA-E429.Tretman oral nan CH5424802 anpeche kwasans timè nan yon fason ki depann de dòz ak ED50 nan 0.46mg / kg. CH5424802, trete nan yon dòz 20mg / kg, ki te koze rapid bès nan timè Chemicalbook pa 168%. Apre 11 jou nan tretman (nan jou 28), volim nan timè nan chak sourit te<30mm3, maintaining effective anti-tumor effect, and no tumor regrowth occurred during 4 weeks of drug-free treatment.

 

 

Si w enterese nan pwodwi nou yo oswa si w gen nenpòt kesyon, tanpri ou lib pou kontakte nou!

 

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Baj popilè: 2-(4-ethylphenyl)-2-methylpropanoic acid cas 1247119-83-0, manifaktirè, founisè, faktori, achte, nan stock

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