5-chloro-1-[(6-benzothiazolyl) sulfonyl]-1H-indole-2-butanoic Asid CAS 927961-18-0

Pwodwi Deskripsyon:

Non pwodwi: 5-chloro-1-[(6-benzothiazolyl) sulfonfonyl]-1H-indole-2-butanoic asid NO: 927961-18-0

 

Sinonim:

Lanifibranor (IVA337);

4-(1-(1,3-Benzothiazol-6-ylsulfonyl) -5-chloro-indol-2-yl) butanoic Asid;

5-chloro-1-[(6-benzothiazolyl) sulfonyl]-1H-indole-2-butanoic asid;

 

Chimik & Pwopriyete fizik:

Aparans: Crystalline solid

Assay: ≥98.0%

Dansite 1.56±0.1 g / cm3 (Predicted)

Fonn pwen: 74 - 80 ° C

Bouyi pwen: 690.9±65.0 ° C (predi)

PKa: 4.69±0.10 (predi)

Flash Point: 371.6±34.3° C

Presyon Vapor: 0.0±2.3 mmHg nan 25 ° C

Endeks refraksyon: 1.727

 

Lanifibranor (IVA-337) se yon pan-PPAR agonist ak EC50 vale de 1537 NM pou HPPAR α, 866 nM pou HPPAR δ ak 206 nM pou HPAR γ, respektivman. Yon PPAR (peroxisome proliferator-aktive resepte) aktivate ak vale EC50 nan 1.5, 0.87, ak 0.21μM pou moun PPARα, PPARσ, ak PPARγ, respektivman.

 

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Baj popilè: 5-chloro-1-[(6-benzothiazolyl) sulfonyl]-1h-indole-2-butanoic asid cas 927961-18-0, manifaktire, founise, faktori, achte, nan stock

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