Anagliptin CAS 739366-20-2

Pwodwi Deskripsyon:

Non pwodwi: Anagliptin CAS NON: 739366-20-2

 

Sinonim:

N-[2-[2-[2S) -2-cyanopyrolidrolidin-1-yl]-2-oxoethyl]-2-methylpropropyl]-2-methylpyrazolo[1,5-a]pirimidine-6-kaboxide;

(S) -N-(2-(2-cyanopyrolidrolidin-1-yl) -2-oksiethylamino) -2-Methylpropropyl) -2-Methylpyrazolo[1,5-a]pirimidine-6-kaboksid;

(R) -N-(2-(2-cyanopyrolidrolidin-1-yl) -2-oksiethylamino) -2-methylpropropyl) -2-methylpyrazolo[1,5-a]pirimidine-6-kaboxamide;

 

Chimik & Pwopriyete fizik:

Aparans: Off-blan solid

Assay: ≥99.00%

Dansite: 1.33±0.1 g / cm3 (Predicted)

Pka: 12.40±0.46 (Prediksyon)

 

Anagliptin se yon peptidaz diptidl-4 (DPP-4) inibitor ki siprime pwopagasyon nan misk vaskile lis ak reyaksyon enflamatwa monosiet. Li tou atire atherosclerosis nan gason apopoprotein E-deficient mis. Anagliptin, ki se make kom Beskoa oswa Suiny, se yon peptidyl diptidyl-IV (DPP-4) inibitor ki te apwouve nan mwa septanm 2012 epi li te lanse nan mwa novanm 2012 nan Japon pou tretman an nan Kalite II dyabet. Dwog la te ko-devlope pa twa konpayi Japine; Kowa, Sanwa Kagaku ak JW famasetik. Anagliptin, ki se plis selektif kont plizye pwotez imen rekonbine pa konparezon a sitagliptin ak Vildagliptin, gen plis pase 10,000-pliye-pliye sou estriktirelman DPP-8 ak DPP-9 anzim.

 

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Baj popilè: anagliptin cas 73936-20-2, manifaktire, founise, faktori, achte, nan stock

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