Elexacaftor CAS 2216712-66-0

Deskripsyon Product:

Non pwodwi:Elexacaftor CAS 2216712-66-0

 

Sinonim:

N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

VX 44

N-[(1,3-Dimethyl-1H-pirazol-4yl)sulfonyl]-6-[3-(3,3,3-trifluoro-2,2dimethylpropoxy)-1H-pyrazol-1-yl]-2-[(4S)2,2,4-trimethyl-1-dyn-boxamide-3,3,3-trifluoro-2,2dimethylpropoxy)

 

 

Pwopriyete Chimik ak Fizik

Aparans: Blan rive nan-blan Solid

Esè: NLT98%

Pwen k ap fonn: 206-208 degre

Dansite: 1.38g / cm³

 

 

Aplikasyon: Elexacaftor se yon eleman nan yon tablèt konbinezon dòz fiks -Vertex Pharmaceuticals devlope ak apwouve pa US Food and Drug Administration (FDA) pou trete mitasyon fibwoz sistik ki pi komen an, F508del. Li se itilize nan konbinezon ak tezacaftor ak ivacaftor. Elexacaftor ak tezacaftor aji kòm korektè CFTR (fibroz sistik transmembrane conductance regilatè), pandan y ap ivacaftor fonksyone kòm yon potentiator CFTR. Terapi konbinezon an gen pou objaktif pou ansanm amelyore pwosesis ak trafik nan pwoteyin CFTR ki defektye epi ogmante aktivite CFTR nan sifas selil la. Devlopman elexacaftor reprezante yon avansman terapetik enpòtan pou pasyan ki gen fibwoz sistik, patikilyèman moun ki gen mitasyon F508del la.

 

 

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Baj popilè: elexacaftor cas 2216712-66-0, manifaktirè, founisè, faktori, achte, nan stock

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