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Ajoute:1002, Huanmao Bilding, No.105, Mengcheng Wout, Hefei Vil, 230061, Lachin

APis ak Entemedye
H3B-6527 CAS 170259-66-2

H3B-6527 CAS 170259-66-2

CAS NON: 1702259-66-2
Fomil molekile: C29H34Cl2N8O4
Molekile Pwa: 629.53700
EINECS NON: NA
MDL NO: MFCD30377210

Pwodwi detay

Pwodwi Deskripsyon:

Non pwodwi: H3B-6527 CAS NON: 1702259-66-2

 

Sinonim:

N-(2-(6-(3-(2,6-dichloro-3,5-dimethoxyphyl) -1-methylureido)pirimidin-4-yl) amino)-5-(4-ethylpiperazin-1-yl)fizyote) acrylamide;

Eisai / H3 Biomedicine;

 

Chimik & Pwopriyete fizik:

Aparans: Solid oswa poud

Assay: ≥99.0%

Bouyi pwen: 832.1±65.0 ° C (predi)

Dansite: 1.373±0.06 g / cm3 (Predicted)

PKa: 11.00±0.70 (Predi)

Flash Point: 457.0±34.3° C

Vapore Presyon: 0.0±3.1 mmHg nan 25 ° C

Endeks refraksyon: 1.665

 

H3B-6527 se yon tre selektif kovalan FGFR4 inibitor ak yon IC50<1.2nm, which="" is="" more="" than="" 250="" times="" more="" selective="" for="" fgfr4="" than="" for="" chemicalbook="" fgfr1-3="" (ic50s="" for="" fgfr1-3="" are="" 320nm,="" 1290nm="" and="" 1060nm,="">

 

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