IPI 549 CAS 1693758-51-8

Deskripsyon pwodwi:

Non pwodwi: IPI 549 CAS NON: 1693758-51-8

Sinonim:

Pyrazolo [1,5-a] pirimidin-3-karboksamid, 2-amino-N - [(1S) -1- [1,2-dihydro-8- [2- (1-methyl-1H-pyrazol-4- yl) ethynyl] -1-oxo-2-phenyl-3-isoquinolinyl] ethyl] -;

Pyrazolo [1,5-a] pirimidin-3-karboksamid, 2-amino-N - [(1S) -1- [1,2-dihydro-8- [2- (1-methyl-1H-pyrazol-4- yl) ethynyl] -1-oxo-2-phenyl-3-isoquinolinyl] ethyl] -;

(S) -2-amino-N- (1- (8 - ((1-methyl-1H-pyrazol-4-il) etinil) -1-oxo-2-fenil-1,2-dihydroisoquinolin-3-il ) etil) pirazolo [1,5-a] pirimidin-3-karboksamid; IPI-549 (IPI549);

Chimik& Pwopriyete fizik:

Aparans: Solid

Egzamen: ≥99.0%

Dansite: 1.37 ± 0.1 g / cm3 (prevwa)

PKa: 10.81 ± 0.46 (prevwa)

IPI-549, ki te pwodwi pa InfinityPharmaceuticals, travay pa bloke molekil PI3kinase-gama (PI3chemicalbookkγ) nan selil suppressor. Rezilta yo, ki te pibliye nan lanati nan 2016, te montre ke bloke molekil sa a chanje balans selil imunosupresè sa yo epi ankouraje deklanchman iminite anti-timè a. IPI-549 se yon inibitè selektif nan phosphoinositol 3 kinase (PI3Kγ). Inibitè PI3Kγ yo ka itilize pou devlope terapi potansyèl pou maladi enflamatwa ak otoiminitè. IPI-549, ki te pwodwi pa enfini famasetik, travay pa bloke molekil PI3 kinase-gama (PI3Kγ) nan selil suppressor, ki ka itilize kòm yon reyaktif selil biyoloji.

Si ou enterese nan pwodwi nou yo oswa ou gen nenpòt kesyon, tanpri ou lib pou kontakte nou!

Pwodwi anba patant yo ofri pou R& D objektif sèlman. Sepandan, responsablite final la manti sèlman ak achtè a.

Baj popilè: ipi 549 cas 1693758-51-8, manifaktirè, founisè, faktori, achte, nan stock

• On: LJN 452 CAS 1383816-29-2
• Pwochen: TP 235 CAS 443104-02-7