Macitentan CAS non: 441798-33-0

Pwodwi deskripsyon

Non pwodwi: Macitentan CAS non: 441798-33-0

 

 

Synonyms:

5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl) oxyethoxy]-N-(propylsulfamoyl) pyrimidin-4-amwen;

N-[5-(4-Bromophenyl)-6-{2-[(5-bromo-2-pyrimidinyl) oxy] ethoxy} -4-pyrimidinyl]-n'-propylsulfuric diamide;

Sulfamide, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl) oxy] ethoxy] -4-pyrimidinyl]-n'-propyl-;

Macitentan;

Actelyon-1;

Opsumit;

 

 

Chimik & pwopriyete fizik

Aparans: blan poud

Épreuves: ≥ 99,0%

Dansite: 1.675 g/cm3

Bouyi pwen: 692.4 ° chat 760 mmHg

Flash pwen: 372.5 ° c

 

 

Macitentan (non komes Opsumit) se yon endothelin récepteurs antagonis (ERA) ki apwouve pou tretman an nan maladi ateryel tansyon wo (PAH). Lot de epok commercialisés yo kom nan 2014 yo bosentan ak ambrisentan. Macitentan se yon PERYOD doub, sa vle di ke li aji kom yon antagonis de endothelin (ET) récepteurs kalite sub, ETA ak ETB. Sepandan, macitentan gen yon 50-pliye ogmante selectivity pou la ETA subtip konpare ak kalite a ETB. Dwog la resevwa apwobasyon nan men manje nan men administrasyon ak medikaman (FDA) nan 13 oktob 2013.

 

 

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Baj popilè: macitentan cas non: 441798-33-0, manifaktire, founise, faktori, achte, nan Stock

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