Memantine Hydrochloride CAS 41100-52-1

Pwodwi Deskripsyon:

Non pwodwi: Memantine Hydrochloride CAS NON: 41100-52-1

 

Sinonim:

1,3-Dimethyl-5-aminoadamantane hydrochoride;

3,5-Dimethyl-1-adamantanamine Hydrochoride;

3,5-Dimethyladamantan-1-amine hydrochoride;

1-Amino-3,5-dimethylamandatane Hydrochoride;

 

Chimik & Pwopriyete fizik:

Aparans : poud blan

Assay: ≥99.0%

Bouyi pwen: 239.8 ° C nan 760 mmHg

Flash Point: 92.3 ° C

Fonn pwen: 292° C

 

Memantine hydrochloride se yon dwog tretman demans devlope pa konpayi an Alman Merz. Li se yon nouvo, ki ba-a-modere afinite, voltaj-depandan, ki pa konpetitif N-methyl-D-aspartate (NMDA) récepteurs antagonist. Li ka bloke récepteurs NMDA ki pa konpetitivman, diminye eksitasyon an anpil nan récepteurs NMDA ki te koze pa glutamate, anpeche apoptosi selil ak amelyore memwa. Li se yon nouvo jenerasyon nan dwog amelyore fonksyon mantal.

Nan mwa fevriye 2002, Komite Medsin Patant Ewopeyen an (CPMP) te apwouve li pou tretman pasyan ki gen maladi modere ak grav maladi Alzheimer la. Li te lanse nan Almay nan mwa Dawou an nan menm ane a e li te apwouve pa Food Ameriken ak Administrasyon Dwog sou Oktob 17, 2003 (FDA) apwouve pou tretman pasyan yo ak modere maladi Alzheimer a grav. Plis rechech montre ke memantine hydrochloride tou se efikas pou pasyan ki gen modere modere maladi Alzheimer a.

maladi Alzheimer a (Alzheimerdisedisease, AD), tou li te ye tankou demans vann, se youn nan maladi yo komen nan granmoun aje, sitou manifeste kom pet memwa ak pwoblem rekonesans, epi li se yon maladi pwogresif neurodegenerative. Kounye a, kolinterase inibitors (fepezil, rivastigmine, galantamine) ak memantine hydrochloride apwouve pou tretman maladi Alzheimer a.

 

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Baj popilè: memantine hydrochloride cas 41100-52-1, manifaktire, founise, faktori, achte, nan stock

• On: 2-Adamantanone CAS 700-58-3
• Pwochen: 1-Acetamido-3,5-Dimethyladamantane CAS 19982-07-1