MK5172 CAS 1350514-68-9

Deskripsyon pwodwi:

Non pwodwi: MK5172 CAS NON: 1350514-68-9

Sinonim:

MK-5172||MK5172;

(1aR,5S,8S,10R,22aR)-5-tèt-butil-N-((1R,2S)-1-{[(cyclopropylsulfonyl)amino]carbonyl}-2-vinylcyclopropyl)-14-methoxy-3, 6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10 ,3,6] dioxadiazacyclononadecino [11,12-b] quinoxaline-8-carboxamide;

(1R,18R,20R,24S,27S)-N-{(1R,2S)-1-[(Cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropyl}-7-methoxy-24-(2-methyl-2-propanyl) -22,25-dioxo-2,21-dioxa-4,11,23,26-tetraazapentacyclo[24.2.1.03,12.05,10.018,20]nonacosa-3,5,7,9,11-pentaene-27-carboxamide , sèl potasyòm;

Chimik& Pwopriyete fizik:

Aparans: Solid blan blan blan

Esè: ≥99.0%

Dansite: 1.38±0.1 g / cm3 (Predi)

Tanperati Depo: Sele nan sèk, Sere nan frizè, anba -20 ℃

Yon konpoze azamacrocyclic ki se yon inibitè proteaz epatit C yo itilize nan konbinezon ak elbasvir (anba non mak Zepatier) pou tretman kwonik jenotip HCV 1 oswa 4 enfeksyon nan granmoun. Grazoprevir (MK-5172) se yon inibitè selektif nan viris Epatit C NS3/4a proteaz ak gwo aktivite atravè jenotip ak varyant rezistan, ak Kis nan 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM. (gt2b), 0.90 nM (gt3a), respektivman.

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Baj popilè: mk5172 cas 1350514-68-9, manifaktirè, founisè, faktori, achte, nan stock

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