Regorafenib (kloridrat) CAS 835621-07-3

Deskripsyon pwodwi:

Non pwodwi: Regorafenib (kloridrat) CAS NON: 835621-07-3

Sinonim:

BAY73-4506 idroklorid;

2-Pyridinecarboxamide, 4- [4 - [[[[4-chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] -3-fluorophenoxy] -N-methyl-, hydrochloride (1: 1);

4- [4 - [[4-kloro-3- (trifluorometil) fenil] karbamoylamino] -3-fluorofenoksi] -N-metilpiridin-2-karboksamid idroklorid;

Chimik& Pwopriyete fizik:

Aparans: Blan solid blan

Egzamen: ≥99.00%

BAY 73-4506 (Regorafenib) se yon inibitè multikinase ak IC50 nan 17, 40 ak 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib Hydrochloride se yon inibitè milti-sib pou VEGFR1 / 2/3, PDGFRβ, Twous, RET ak Raf-1 ak IC50s nan 13 / 4.2 / 46, 22, 7, 1.5 ak 2.5 nM, respektivman.

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Baj popilè: regorafenib (hydrochloride) cas 835621-07-3, manifaktirè, founisè, faktori, achte, nan stock

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