Riboklib CAS 1211441-98-3

Pwodwi Deskripsyon:

Non pwodwi: Riboklib CAS NON: 1211441-98-3

 

Sinonim:

7-cyclopentyl-N,N-dimethyl-2-((5-(pirazin-1-yl) piridin-2-yl) amino) -7H-pyrrolo [2,3-d]pirimidine-6-kaboksid;

LEE 011;

 

Chimik & Pwopriyete fizik:

Aparans: blan pou poud blan

Assay: ≥99.0%

Dansite: 1.39g / cm3

Bouyi pwen: 730.8 ° C nan 760 mmHg

Flash Point: 395.8 ° C

Solibilite: Soluble nan DMSO, pa solib nan dlo.

 

Deskripsyon: Riboklib Gratis Baz, tou li te ye kom LEE011, se yon siklin oralman ki disponib siklin-depandan kinaz (CDK) inibite vize siklin D1 / CDK4 ak siklin D3 / CDK6 selil wout, ak aktivite potansyel antioplastik. CDK4 / 6 inibiteUR LEE011 espesyalman inibit CDK4 ak 6, kidonk entedi retinoblastoma (Rb) pwoteyin fosfo. Anpeche Phosphorylation Rb anpeche CDK-medyate G1-S faz tranzisyon, kidonk arrese sik selil la nan faz G1, souprime sentez ADN ak entedi kwasans selil kanse. Overexpression nan CDK4 / 6, jan yo we nan seten kalite kanse, lakoz deregilasyon sik selil.

 

KA ki gen rapo #

121441-98-3 (Riboklib baz gratis)

121443-80-9 (Riboklik hydrochoride)

1374639-75-4 (Riboklib sucinate)

 

 

Si ou enterese nan pwodwi nou yo oswa ou gen nenpot kesyon, tanpri santi yo lib yo kontakte nou!

 

 

Pwodwi anba patant yo ofri pou R & D rezon selman. Sepandan, denye responsablite a bay manti selman ak achte a.

 

 

 

Baj popilè: riboklib cas 1211441-98-3, manifaktire, founise, faktori, achte, nan stock

• On: Tetrabutylammonyom Bromide CAS 1643-19-2
• Pwochen: 3-Bromo-2-methylbenzoic Asid CaS 76006-33-2