Kontakte:Errol Zhou (Mesye.)
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Nimewo CAS:879085-55-9
Fòmil molekilè: C19H14Cl2N2O3S
Pwa molekilè: 421.3
EINECS NON: 806-752-3
MDL NON: MFCD12407408
Deskripsyon Product:
Non pwodwi: Vismodegib CAS 879085-55-9
Sinonim:
2-Kloro-N-[4-kloro{-3-({2-piridinil)fenil]-4-(methylsulfonyl)benzamid;BROMO-1-NAPHTA
BenzaMide, 2-kloro-N-[{4-kloro{-3-({2-piridinil)fenil]-4-(Methylsulfonyl)-;
VisModegib (GDC-0449);
Pwopriyete Chimik ak Fizik
Aparans: Blan ak Off-Blan Solid
Esè: 99% +
Pwen bouyi: 561.6±50.0 degre
Pwen k ap fonn: 179-181 degre
Pwa molekilè: 421.3
Dansite: 1.440
Pka:10.72±0.70
Estabilite: Ki estab pou 2 ane soti nan dat achte jan yo apwovizyone. Solisyon nan DMSO oswa etanòl ka estoke nan -20 degre pou jiska 3 mwa.
Aplikasyon:
Vimodej targets SMO protein and inhibits Gli activation, thereby inhibiting downstream gene transcription and expression.For the treatment of locally progressive or metastatic basal cell carcinoma in adults who have recurred after surgery or are not well treated with surgery or radiotherapy; One of the most common skin cancers is basal cell carcinoma (BCC), which originates in the surface layer of the skin and does not cause pain to patients. The risk was greatest for skin diseases that were regularly exposed to the sun or ultraviolet light. The development and listing of Vimedji has brought good news to patients with BCC, and its clinical role is important and the target market is huge, and it has to grow into a "giant bomb" class (>$1 milya) dwòg nan tan kap vini an.
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